Rabbit Anti-ART1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ART1
IR:Immunogen Range:101-200/320
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:417
Swiss Prot:P52961
Source:KLH conjugated synthetic peptide derived from human PHEMX/ART1:101-200/320
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin αIIb/Integrin β3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate “outside-in” signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： ART1;FLJ17158;FLJ97586;MGC22455;Pan hematopoietic ex;PHEMX;PHMX;TSPAN32;
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