Rabbit Anti-KCNF1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:KCNF1
IR:Immunogen Range:161-260/494
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3754
Swiss Prot:Q9H3M0
Source:KLH conjugated synthetic peptide derived from human KCNF1:161-260/494
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： KCNF1;IK8;KCNF 1;KCNF;Kcnf1;kH1;KV5.1;KCNF1_HUMAN;
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