Rabbit Anti-CCBR1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CCBR1
IR:Immunogen Range:201-300/501
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:23657
Swiss Prot:Q9UPY5
Source:KLH conjugated synthetic peptide derived from human xCT/CCBR1:201-300/501
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： CCBR1;CCBR1;SLC7A11;Solute carrier famil;olute carrier family;xCT;Solute carrier famil;XCT_HUMAN;
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