Rabbit Anti-FADD Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FADD
IR:Immunogen Range:51-150/205
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:14082
Swiss Prot:Q13158
Source:KLH conjugated synthetic peptide derived from mouse FADD:51-150/205
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Predicted to enable several functions, including caspase binding activity; death effector domain binding activity; and tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; negative regulation of activation-induced cell death of T cells; and positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand; motor neuron apoptotic process; and regulation of programmed cell death. Predicted to be located in several cellular components, including cell body; cytosol; and membrane raft. Predicted to be part of CD95 death-inducing signaling complex and ripoptosome. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in leukemia. Orthologous to human FADD (Fas associated via death domain). [provided by Alliance of Genome Resources, Apr 2022]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Mouse
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關鍵字: FADD;MORT1;GIG3;IMD90;FAS-associating deat;Mediator of receptor;Fas死亡結構域相關蛋白抗體;FADD_MOUSE;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學實驗室產(chǎn)品生物科技企業(yè)。主營產(chǎn)品:試劑盒,ELISA試劑盒,抗體,重組蛋白,血清,胎牛血清,細胞,原代細胞 細胞培養(yǎng)試劑,常用生化試劑。