Rabbit Anti-Tap1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Tap1
IR:Immunogen Range:501-600/808
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6890
Swiss Prot:Q03518
Source:KLH conjugated synthetic peptide derived from human Tap1/ABCB2:501-600/808
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:1000-5000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg /Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Tap1;ABC transporter MHC ;ABC17;ABCB2;APT1;PSF1;RING 4;TAP1_HUMAN;
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