Rabbit Anti-PTGEs/Prostaglandin E Synthase Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:PTGEs/Prostaglandin E Synthase
IR:Immunogen Range:85-152/152
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9536
Swiss Prot:O14684
Source:KLH conjugated synthetic peptide derived from human PTGEs:85-152/152
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Prostaglandin E synthase catalyses conversion of COX derived PGH2 to PGE2. It is a member of the MAPEG family. It may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain during inflammatory responses.
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： PTGEs/Prostaglandin ;Glutathione S transf;MGC10317;MGST IV; MGST1 L1;MGST1 like 1;MGST1L1;PTGES_HUMAN;
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