Rabbit Anti-CD146 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CD146
IR:Immunogen Range:201-300/646
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4162
Swiss Prot:P43121
Source:KLH conjugated synthetic peptide derived from human CD146:201-300/646
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:MCAM (MUC18 antigen, CD146), a member of the immuoglobulin superfamily, is an intrinsic membrane glycoprotein of 110-120 kDa found on the surface of endothelial cells, bone marrow fibroblasts and various melanomas. MCAM (Melanoma adhesion molecule) has been used as a marker of tumor progression in human melanoma because expression in those tumors correlates strongly with poor prognosis and the development of metastic disease. In addition, a number of human T, B and myeloid leukemic cell lines seem to express MCAM. The close structural relationship with N-CAM and related molecules suggests that MCAM may be also a developmentally regulated cell adhesion.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CD146;A32 antigen;CD 146;CD146 antigen;Cell surface glycopr;Cell surface glycopr;MUC18;MUC18_HUMAN;
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