Rabbit Anti-GRK2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GRK2
IR:Immunogen Range:601-689/689
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:156
Swiss Prot:P25098
Source:KLH conjugated synthetic peptide derived from human GRK2:601-689/689
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Guinea Pig
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： GRK2;G-protein coupled re;ADRBK 1;Adrenergic beta rece;BARK;Beta ARK 1;FLJ16718;ARBK1_HUMAN;
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