Rabbit Anti-EAAT2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:EAAT2
IR:Immunogen Range:101-200/574
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6506
Swiss Prot:P43004
Source:KLH conjugated synthetic peptide derived from human EAAT2:101-200/574
Purification:affinity purified by Protein A
Storage:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
Sheep
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： EAAT2;Excitatory amino aci;Excitotoxic amino ac;GLT1;SLC1A2;Sodium-dependent glu;Solute carrier famil; dependent glutamate;
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