Rabbit Anti-LECT1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:LECT1
IR:Immunogen Range:231-334/334
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:11061
Swiss Prot:O75829
Source:KLH conjugated synthetic peptide derived from human LECT1:231-334/334
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The LECT1 gene encodes a glycosylated transmembrane protein which is cleaved to form a mature, secreted protein. The N terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein, although no biological activity has yet been defined for it. The C terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell derived chondromodulin 1 or chemotaxin 1. The mature protein inhibits angiogenesis and promotes chondrocyte growth. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： 7516R;Chondromodulin I;BRICD3;BRICHOS domain conta;CHM1;chondromodulin;ECT 1;LECT1_HUMAN;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學實驗室產(chǎn)品生物科技企業(yè)。主營產(chǎn)品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。