Rabbit Anti-phospho-AMPK beta 1 + AMPK beta 2 (Ser182/Ser184) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-AMPK beta 1 + AMPK beta 2 (Ser182/Ser184)
IR:Immunogen Range:SS(p-S)PP
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5564
Swiss Prot:Q9Y478
Source:KLH conjugated synthesised phosphopeptide derived from human AMPK beta 1 around the phosphorylation site of Ser182:SS(p-S)PP
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： phospho-AMPK beta 1 ; PRKAB1(phospho S182;PRKAB1(phospho-S182);Phospho-Stat3（pTyr70;p-AMPK beta 1(S182);MPK beta 2(phospho S;HAMPKb;AAKB1_HUMAN;
上海滬震實(shí)業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實(shí)驗(yàn)室產(chǎn)品生物科技企業(yè)。主營產(chǎn)品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細(xì)胞，原代細(xì)胞 細(xì)胞培養(yǎng)試劑，常用生化試劑。