Rabbit Anti-Phospho-PLCG1 (Tyr783) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-PLCG1 (Tyr783)
IR:Immunogen Range:GF(p-Y)VE
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5335
Swiss Prot:P19174
Source:KLH conjugated Synthesised phosphopeptide derived from human PLC gamma 1 around the phosphorylation site of Tyr783:GF(p-Y)VE
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Horse
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： Phospho-PLCG1 (Tyr78;PLC gamma 1;Phospholipase C 148;Phospholipase C gamm;phospholipase C-148;Phospholipase C-II;PLC 148;PLCG1_HUMAN;
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