Rabbit Anti-Phospho-NFKB1 (Ser927) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-NFKB1 (Ser927)
IR:Immunogen Range:ND(p-S)VC
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4790
Swiss Prot:P19838
Source:KLH conjugated Synthesised phosphopeptide derived from rat NFKB1 around the phosphorylation site of Ser927:ND(p-S)VC
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Rat
Hamster
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-NFKB1 (Ser92;Nuclear factor NF-ka;KBF1;EBP-1;NFkB p105 / p50;NFkB p105/p50;CVID12;NFKB1_HUMAN;
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