Rabbit Anti-PLCZ1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:
Host:Rabbit
Target Protein:PLCZ1
IR:Immunogen Range:351-450/608
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:89869
Swiss Prot:Q86YW0
Source:KLH conjugated synthetic peptide derived from human PLCZ1:351-450/608
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, PLCZ1 hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. It triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. PLCZ1 is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. It may exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： PLCZ1;1 phosphatidylinosit; bisphosphate phosph;Phosphoinositide pho;FAAHPhospholipase C ;C zeta 1;PLC zeta 1;Testis development p;
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