Rabbit Anti-Integrin alpha 6 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Integrin alpha 6
IR:Immunogen Range:1031-1130/1130
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3655
Swiss Prot:P23229
Source:KLH conjugated synthetic peptide derived from human Integrin alpha 6:1031-1130/1130
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Integrin alpha 6;Integrin alpha-6 Al;VLA 6 alpha subunit;VLA 6;CD49f;Processed integrin a;ITGA6;ITA6_HUMAN;
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