Rabbit Anti-HAS1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:HAS1
IR:Immunogen Range:501-578/578
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3036
Swiss Prot:Q92839
Source:KLH conjugated synthetic peptide derived from human Hyaluronan synthase 1:501-578/578
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by beta-1,3 and beta-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS1 mRNA shows predominant expression in bone marrow mesenchymal progenitor cells and synovial cells.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： HAS1;HA synthase 1;HAS;HAS1;HuHAS1;Hyaluronan synthase ;Hyaluronic acid synt;HAS1_HUMAN;
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