Rabbit Anti-KDM5B Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:KDM5B
IR:Immunogen Range:65-165/1544
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10765
Swiss Prot:Q9UGL1
Source:KLH conjugated synthetic peptide derived from human KDM5B/PLU1/Jarid1B:65-165/1544
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3ug/test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： KDM5B;Cancer/testis antige;CT31;istone demethylase J;JARID1B;Jumonji AT rich inte;Kdm5b;KDM5B_HUMAN;
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