Rabbit Anti-GPR19/GPR4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GPR19/GPR4
IR:Immunogen Range:201-300/362
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2842
Swiss Prot:Q15760
Source:KLH conjugated synthetic peptide derived from human G protein coupled receptor 19:201-300/362
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. GPR19, an orphan receptor, shows elevated expression during embyronic development of the nervous sytem as well as in specific regions of adult mouse brain, including the olfactory bulb, the hippocampus, hypothalamic nuclei and the cerebellum. The GPR19 gene maps to a location on chromosome 12, which is a frequent target for rearrangement in cancer cells and involved in childhood acute lymphoblastic leukemia (ALL).
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： GPR19/GPR4;GPCR GPR4;G protein coupled re;G protein coupled re;G-protein coupled re;G-protein coupled re;GPR19;GPR4_HUMAN;
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