Rabbit Anti-GAB2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GAB2
IR:Immunogen Range:601-676/676
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9846
Swiss Prot:Q9UQC2
Source:KLH conjugated synthetic peptide derived from human Gab2:601-676/676
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:2000-5000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg /test)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： GAB2;Gab2;Grb 2 associated bin;GRB 2 associated bin;Grb2 associated bind;GRB2 associated bind; GRB2 associated bin;KIAA0571;
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