Rabbit Anti-Complement component C9b Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Complement component C9b
IR:Immunogen Range:251-350/559
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:735
Swiss Prot:P02748
Source:KLH conjugated synthetic peptide derived from human Complementcomponent C9b:251-350/559
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(1ug/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Sheep
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Complement component;C9b;Complement ;component ;component C9;Complementcomponent ;C9b;CO9_HUMAN;
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