Rabbit Anti-CTLA4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CTLA4
IR:Immunogen Range:141-223/223
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1493
Swiss Prot:P16410
Source:KLH conjugated synthetic peptide derived from human CTLA-4:141-223/223
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CTLA4;CD152; CD152 antigen;Celiac disease 3;CELIAC3;CTLA ;Cytotoxic T cell ass;CTLA4_HUMAN;
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