Rabbit Anti-STAT5 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:STAT5
IR:Immunogen Range:61-160/794
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6776
Swiss Prot:P42229
Source:KLH conjugated synthetic peptide derived from human STAT5:61-160/794
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： STAT5;MGF;STAT 5;STAT 5A;STAT 5B;STAT5A;STA5B_HUMAN;STA5A_HUMAN;
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