Rabbit Anti-Cytochrome P450 17A1 Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Cytochrome P450 17A1
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:1586
Swiss Prot:P05093
Source:Recombinant human Cytochrome P450 17A1:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family; it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： Cytochrome P450 17A1;CPT7;CYP17A1;CYP17;Cytochrome P450 17A1;CYPXVII;Cytochrome P450 fami;Cytochrome p450;
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