Host:Rabbit
Target Protein:Gemin 2
IR:Immunogen Range:101-200/280
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8487
Swiss Prot:O14893
Source:KLH conjugated synthetic peptide derived from human Gemin 2:101-200/280
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)ELISA(1:5000-10000)IHC-P(1:100-500)IHC-F(1:100-500)IF(1:100-500)
Cross Reactive Species:HumanMouseRatPigHorseRabbit
本產品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用!
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