Host:Rabbit
Target Protein:OCLN
IR:Immunogen Range:431-522/522
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:18260
Swiss Prot:Q61146
Source:KLH conjugated synthetic peptide derived from mouse OCLN:431-522/522
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(2μg/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Guinea Pig
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用！
關(guān)鍵字： Occludin;Ocl;BLCPMG;PPP1R115;PTORCH1;
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