中文名稱:Anti-LOX 1 antibody-凝集素樣氧化型低密度脂蛋白受體抗體 | 英文名稱:LOX 1 |
品牌: 滬震生物 | 產(chǎn)地: 中國/上海 |
保存條件: -20°C | 純度規(guī)格: > 99% |
產(chǎn)品類別: 抗體 一抗 | |
抗體名: Lectin-type oxidized LDL receptor 1; OLR1; lectin-like low density lipoprotein receptor-1; Oxidized low-density lipoprotein receptor 1; Ox-LDL receptor 1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; LOX-1; BLOX1; Contains: Oxidized low-density lipoprotein receptor 1, soluble form A; Oxidized low-density lipoprotein receptor 1, soluble form B; OLR1_HUMAN. | 靶點: 詳見說明書 |
宿主: Rabbit | 適應(yīng)物種: 詳見說明書 |
克隆性: 詳見說明書 | 濃度: 1mg/ml |
應(yīng)用范圍: WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. | 標(biāo)識物: 詳見說明書 |
形態(tài): 液體 | 亞型: IgG1 |
免疫原: 詳見說明書 | 貨號: HZ-R2044 |
用途范圍: 科研使用 | 規(guī)格: 50ul/100ul/200ul |
是否進(jìn)口: 否 | 是否單克隆: 詳見說明書 |
保質(zhì)期: 12個月 | 抗原來源: 詳見說明書 |
標(biāo)記物: 詳見說明書 | 產(chǎn)品用途: WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
Host:Rabbit
Target Protein:LOX 1
IR:Immunogen Range:201-273/273
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:100009322
Swiss Prot:Q9XTA8
Source:KLH conjugated synthetic peptide derived from rabbit LOX-1:201-273/273
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Rabbit
本產(chǎn)品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用!
成立日期 | 2014-05-08 (11年) | 注冊資本 | 100萬元整 |
員工人數(shù) | 10-50人 | 年營業(yè)額 | ¥ 100萬以內(nèi) |
主營行業(yè) | 生化試劑,細(xì)胞培養(yǎng),蛋白組學(xué),分子生物學(xué),細(xì)胞生物學(xué) | 經(jīng)營模式 | 工廠,試劑,定制,服務(wù) |
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