Host:Rabbit
Target Protein:Growth hormone receptor
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:2690
Swiss Prot:P10912
Source:KLH conjugated synthetic peptide derived from human Growth hormone receptor:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500)
IHC-P(1:50-200)
ICC(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
.
本產(chǎn)品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！
關(guān)鍵字： GHBP;GHR;GHR_HUMAN;GH receptor;Growth hormone recep;
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