Product Name：Compstatin
CAS No.：206645-99-0
Synonyms：坎普他汀多肽原料
Catalog No.：130P12
Brand：HongTide（上海鴻肽生物）
Description：Compstatinis是一種具有較強(qiáng)穩(wěn)定性的特異性抑制劑多肽，序列的N端被乙酰化后，可以有效避免多肽在生物體內(nèi)被酶降解。Compstatin的主要生理功能是能夠完全抑制肝素/魚精蛋白誘導(dǎo)的補(bǔ)體激活，而對(duì)心率或全身性血管、中心靜脈和肺動(dòng)脈壓沒有副作用，同時(shí)Compstatin是一種安全有效的補(bǔ)體抑制劑，在臨床心臟手術(shù)中，具有抑制補(bǔ)體激活的潛力。在多肽合成方面，Compstatin屬于收率較高的多肽。
Compstatins is a specific inhibitor peptide with strong stability. After acetylation of the N-terminus of the sequence, it can effectively prevent the peptide from being degraded by enzymes in the organism. The main physiological function of Compstatin is to completely inhibit complement activation induced by heparin/protamine, without any side effects on heart rate or systemic vascular, central venous, and pulmonary arterial pressure. Compstatin is a safe and effective complement inhibitor with the potential to inhibit complement activation in clinical cardiac surgery. In terms of peptide synthesis, Compstatin belongs to the category of peptides with higher yields.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | ICVVQDWGHHRCT-NH2(Disulfide bridge: Cys2-Cys11) |
Sequence(3-letter code) | H-Ile-Cys-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys-Thr-NH2(Disulfide bridge: Cys2-Cys11) |
Peptide Structure | 
|
Molecular Formula | C66H99N23O17S2 |
Molecular Weight | 1550.77 |
訂購聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關(guān)鍵字： 206645-99-0;Compstatin;坎普他汀多肽原料;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。