Product Name：Ganirelix
CAS No.：124904-93-4；123246-29-7
Synonyms：Ganirelix acetate；醋酸加尼瑞克
Catalog No.：218P138
Brand：HongTide（上海鴻肽生物）
Description：醋酸加尼瑞克是一合成的與內(nèi)源性促性腺素釋放素（GnRH）（又稱促黃體生成素釋放素，LHRH）類似的十肽化合物，包含大量的非天然氨基酸，是GnRH的拮抗劑，其可競爭性拮抗促性腺的GnRH受體，從而變異途徑，引起快速、可逆性地抑制促性腺激素（黃體生成素LH和促卵泡激素FSH）分泌。 醋酸加尼瑞克抑制垂體分泌LH比抑制分泌FSH更顯著，從而降低性激素的產(chǎn)生。
Ganirelix acetate is a synthesized decapeptide compound similar to endogenous gonadotropin releasing hormone (GnRH) (also known as luteinizing hormone releasing hormone, LHRH). It contains a large amount of non natural amino acids and is an antagonist of GnRH. It can competitively antagonize the GnRH receptor of the gonadotropin, thereby mutating the pathway and causing rapid and reversible inhibition of gonadotropin secretion (luteinizing hormone LH and follicle stimulating hormone FSH). Acetic acid plus niarik inhibits pituitary LH secretion more significantly than FSH secretion, thereby reducing the production of sex hormones.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-D-Nal-[D-(PCL)Phe]-D-Pal-S-Y-D-Har(Et2)-L-Har(Et2)-P-d-A-NH2 |
Sequence(3-letter code) | Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-Tyr-D-Har(Et2)-Leu-Har(Et2)-Pro-D-Ala-NH2 |
Peptide Structure | 
|
Molecular Formula | C80H113ClN18O13 |
Molecular Weight | 1570.35 |
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上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關(guān)鍵字： 124904-93-4;123246-29-7;Ganirelix;加尼瑞克;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。