Product Name：β-Defensin 2 (human)
CAS No.：372146-20-8
Synonyms：β-Defensin 4A (human)；Skin-antimicrobial peptide 1 (human)；β-防御素2，人源
Catalog No.：112P22
Brand：HongTide（上海鴻肽生物）
Description：β-防御素作為抗菌肽的一種,是一類富含精氨酸的陽離子的環(huán)狀多肽，序列中含有41個氨基酸，并且?guī)в腥龑Χ蜴I，廣泛分布于動物、植物和昆蟲體內。體外抑菌試驗表明,防御素能對革蘭氏陽性和陰性細菌、真菌、分枝桿菌、螺旋體、披膜病毒等病原微生物產生較強的殺傷作用，甚至對支原體、衣原體、螺旋體以及一些惡性細胞(如腫瘤細胞)和艾滋病病毒也具有殺傷作用。運用基因工程技術表達而大量生產的防御素無毒副作用，也不會使病原微生物菌株變異而產生抗藥性,且具有廣泛的抗性譜。β-Defensin 2 (human)由41個氨基酸組成，序列中有6個半胱氨酸，并且在自然條件下隨機形成二硫鍵，結構相對穩(wěn)定。
β- As a kind of antibacterial peptide, defensin is a kind of cyclic peptide rich in arginine cation. It contains 41 amino acids in its sequence and has three pairs of disulfide bonds. It is widely distributed in animals, plants and insects. In vitro bacteriostasis test shows that defensin can have a strong killing effect on gram-positive and negative bacteria, fungi, mycobacteria, spirochetes, drape virus and other pathogenic microorganisms, even against mycoplasma, chlamydia, spirochetes, some malignant cells (such as tumor cells) and AIDS virus. The defensin, which are expressed by genetic engineering technology and produced in large quantities, have no side effects and will not cause the variation of pathogenic microorganism strains to produce drug resistance, and have a broad resistance spectrum. β- Defensin 2 (human) is composed of 41 amino acids, with 6 cysteine in the sequence, and randomly forms disulfide bonds under natural conditions, with a relatively stable structure.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP(Disulfide bonds, air oxidized) |
Sequence(3-letter code) | H-Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro-OH (Disulfide bonds, air oxidized) |
Peptide Structure | 
|
Molecular Formula | C188H305N55O55S6 |
Molecular Weight | 4328.23 |
訂購聯(lián)系方式：
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關鍵字： 372146-20-8;β-Defensin 2 (human);β-防御素2，人源;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現(xiàn)有產品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內外眾多科研工作者提供了優(yōu)質的服務及產品。