Product Name:Pardaxin
CAS No.:67995-63-5
Synonyms:豹鰨毒素
Catalog No.:218P008
Brand:HongTide(上海鴻肽)
Description:豹鰨毒素(pardaxin)是一種具有α-螺旋結(jié)構(gòu)的多肽,包含33個氨基酸,因最早在石紋豹鰨體內(nèi)被發(fā)現(xiàn)而得名。豹鰨背鰭、腹鰭和臀鰭基部有超過兩百個毒腺由小孔通向體外,豹鰨毒素就從這里產(chǎn)生并被分泌到體表黏液中去,這種毒素能夠破壞細(xì)胞中的磷脂雙分子層,改變細(xì)胞的滲透性,引起細(xì)胞溶解釋放內(nèi)容物,并像表面活性劑一樣降低細(xì)胞表面的張力。Pardaxin是一種抗菌、凋亡和神經(jīng)毒性離子載體多肽。能在脂質(zhì)膜上形成孔,同時能誘導(dǎo)半胱天冬酶依賴性和ROS介導(dǎo)的細(xì)胞凋亡;刺激花生四烯酸(Asc 916)和類花生酸的鈣非依賴性PLA2釋放,在體內(nèi)非?;钴S。
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code)
GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE
Sequence(3-letter code)
H-Gly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Gly-Gln-Glu-OH
Peptide Structure
Molecular Formula
C154H248N36O45
Molecular Weight
3323.88
訂購聯(lián)系方式:
上海鴻肽生物科技有限公司
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郵箱:sales1@hongtide.com
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鴻肽生物