產(chǎn)品屬性：

Cas No.1622849-43-7

別名 N/A

化學(xué)名 N/A

分子式 C??H??F?N?O?

分子量 397.38

溶解度 Soluble in DMSO

儲(chǔ)存條件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM [1].

IC50: 6.3 nM (RIP1 kinase )[1]

GSK3145095 potently blocks the TNF response as shown by determination of overall cell viability as measured by cellular ATP levels (IC50 = 1.6 nM), cell death as measured by LDH release (IC50 = 0.5 nM) and RIP1-dependent inflammatory cytokine MIP-1β production, either as absolute levels for protein, or fold changes in mRNA expression (IC50 = 0.4 nM) [1].