產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號(hào)
型號(hào)
GSK-843
5mg
1601496-05-2
EY-Y0165703
Cas No.1601496-05-2
別名 N/A
化學(xué)名 N/A
分子式 C19H15N5S2
分子量 377.49
溶解度 Soluble in DMSO
儲(chǔ)存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM[1]. IC50: 6.5 nM (RIP3)[1]
[1]. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
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