產(chǎn)品屬性：
產(chǎn)品名稱 | 規(guī)格 | CAS號 | 型號 |
Chartreusin | 1mg 5mg | 6377-18-0 | EY-Y0165412 |
Cas No.6377-18-0
別名 N/A
化學(xué)名 10-[[6-deoxy-2-O-(6-deoxy-3-O-methyl-α-D-galactopyranosyl)-β-D-galactopyranosyl]oxy]-6-hydroxy-1-methyl-benzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione
分子式 C32H32O14
分子量 640.6
溶解度 Acetone: soluble,DMSO: 10 mg/ml,Methanol: slightly soluble
儲存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Chartreusin is an antibiotic originally isolated from S. chartreusis with diverse biological activities. It inhibits growth of S. aureus, B. subtilis, M. luteus, M. flavus, B. fragilis, C. difficile, C. perfringens, and P. acnes (MICs = 0.4-12.5 μg/ml). Chartreusin binds to DNA and induces electrophoretic shifts in both supercoiled and nicked plasmid DNA. It also inhibits strand-passing activity of topoisomerase II in a P4 unknotting assay. Chartreusin inhibits protein synthesis in chick embryo fibroblasts (CEFs) and mouse fibroblast 3T6 cells (IC50s = 7 and 70 μM, respectively). It is cytotoxic to human lung carcinoma A549 cells in vitro (IC50 = 95 nM) and increases median survival in P388 leukemia and B16 melanoma mouse tumor models when administered at a dose of 10 mg/kg per day.
關(guān)鍵字： 6377-18-0;C32H32O14;Chartreusin;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要從事免疫學(xué)、分子生物學(xué)和常規(guī)生化試劑等為一體的科研產(chǎn)品銷售企業(yè)，公司自成立以來，秉承""全心全意服務(wù)于科研工作者""的企業(yè)理念，立足生物科技領(lǐng)域，運用生物技術(shù)和科研試劑，發(fā)展現(xiàn)代生物科技，為各類大中小醫(yī)院及其它醫(yī)療機構(gòu)、高等院校、科研院所、企事業(yè)單位提供優(yōu)質(zhì)的產(chǎn)品，服務(wù)生物科技領(lǐng)域的科學(xué)研究人員。
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