產(chǎn)品屬性：
產(chǎn)品名稱 | 規(guī)格 | CAS號 | 型號 |
Echinosporin | 1 mg | 79127-35-8 | EY-Y0165297 |
Cas No.79127-35-8
別名 N/A
化學名 N/A
分子式 C10H9NO5
分子量 223.2
溶解度 DMF: soluble,Methanol: soluble,Water: soluble
儲存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Echinosporin is a bacterial metabolite originally isolated from Streptomyces echinosporus that has antibacterial and anticancer activities.1,2,3 It is active against P. vulgaris, S. typhosa, S. sonnei, E. coli, and B. subtilis (MICs = 100, 100, 100, 200, and 400 μg/ml, respectively).1 Echinosporin induces cell cycle arrest at the G2/M phase and apoptosis in, as well as inhibits proliferation of, HCT-15 human colorectal cancer cells (IC50s = 1.7, 1.75, and 247 μM, respectively).2 It inhibits tumor growth in murine P388 leukemia and Meth 1 fibrosarcoma models when administered at doses ranging from 10 to 80 mg/kg.3
1.Sato, T., Kawamoto, I., Oka, T., et al.A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterizationJ. Antibiot. (Tokyo)35(3)266-271(1982) 2.Cui, C.B., Liu, H.B., Gu, J.Y., et al.Echinosporins as new cell cycle inhibitors and apoptosis inducers from marine-derived Streptomyces albogriseolusFitoterapia78(3)238-240(2007) 3.Morimoto, M., and Imai, R.Antitumor activity of echinosporinJ. Antibiot. (Tokyo)38(4)490-495(1985)
關(guān)鍵字： 79127-35-8;C10H9NO5;Echinosporin;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要從事免疫學、分子生物學和常規(guī)生化試劑等為一體的科研產(chǎn)品銷售企業(yè)，公司自成立以來，秉承""全心全意服務于科研工作者""的企業(yè)理念，立足生物科技領(lǐng)域，運用生物技術(shù)和科研試劑，發(fā)展現(xiàn)代生物科技，為各類大中小醫(yī)院及其它醫(yī)療機構(gòu)、高等院校、科研院所、企事業(yè)單位提供優(yōu)質(zhì)的產(chǎn)品，服務生物科技領(lǐng)域的科學研究人員。
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