產(chǎn)品屬性：

Cas No.22644-96-8

別名 N/A

化學名 N/A

分子式 C16H30O

分子量 238.4

溶解度 DMF: 30 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml

儲存條件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal is a sphingolipid degradation product resulting from the action of S1P lyase. It can be further oxidized to (2E)-hexadecenoic acid by long-chain fatty aldehyde dehydrogenase prior to activation via coupling to coenzyme A. (E)-2-Hexadecenal has been shown to induce cytoskeletal reorganization that results in cell rounding, detachment, activation of downstream JNK targets, and eventual apoptosis in various cell types. It reacts readily with deoxyguanosine and DNA to form aldehyde-derived DNA adducts.