產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
(D)-PPA 1
1 mg
1620813-53-7
EY-Y0164985
Cas No.1620813-53-7
別名 N/A
化學名 N/A
分子式 C70H98N20O21
分子量 1555.67
溶解度 Soluble in DMSO
儲存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.
Chang et al (2015) Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl. 54 11760 PMID:26259671
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