產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號(hào)
型號(hào)
Ganglioside GD3 Mixture (sodium salt)
500μg 1mg
62010-37-1
EY-Y0164465
Cas No.62010-37-1
別名 N/A
化學(xué)名 N/A
分子式 C70H123N3O29?2Na (for Sphingosine C18:1)
分子量 1516.7
溶解度 Chloroform:Methanol (1:1): Soluble,Water: Soluble
儲(chǔ)存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increases both cell proliferation and invasion in vitro. Ganglioside GD3-deficient adult mice exhibit progressive loss of the neural stem cell (NSC) pool and impaired neurogenesis. Ganglioside GD3 mixture contains ganglioside GD3 molecular species with C18:1 and C20:1 sphingoid backbones.
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