產(chǎn)品屬性：

Cas No.582314-48-5

別名 N/A

化學(xué)名 N/A

分子式 C17H15Cl2NO2

分子量 336.2

溶解度 DMF: 30 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2)(1:2:): .25 mg/ml,Ethanol: 5 mg/ml

儲(chǔ)存條件 Store at -20°C
General tips  For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition     Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 μM. These apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs.