產(chǎn)品屬性:
產(chǎn)品名稱 | 規(guī)格 | CAS號 | 型號 |
7α-Thiospironolactone | 500μg 1mg 5mg 10mg | 38753-76-3 | EY-Y0163668 |
Cas No.38753-76-3
別名 N/A
化學(xué)名 N/A
分子式 C22H30O3S
分子量 374.5
溶解度 Ethanol: soluble
儲(chǔ)存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
7α-Thiospironolactone (7α-Thio-SL) is an active metabolite of the synthetic steroid spironolactone.1 In vivo, 7α-thio-SL (100 mg/kg) decreases plasma testosterone and estradiol levels in male dogs.2 It reduces mercuric chloride-induced nephrocalcinosis and mortality in rats.3
1.Los, L.E., Coddington, A.B., Ramjit, H.G., et al.Identification of spironolactone metabolites in plasma and target organs of guinea pigsDrug Metab. Dispos.21(6)1086-1090(1993) 2.Menard, R.H., Loriaux, D.L., Bartter, F.C., et al.The effect of the administration of spironolactone on the concentration of plasma testosterone, estradiol and cortisol in male dogsSteroids31(6)771-782(1978) 3.Szabo, S., and Gagnon, M.J.The protective effect of sulfur-containing steroids against nephrocalcinosis induced by mercuric chloride in ratsGen. Pharmacol.14(2)269-272(1983)
關(guān)鍵字: 38753-76-3;C22H30O3S;7α-Thiospironolacton;
上海一研生物科技有限公司Shanghai yiyan bio-technology Co. Ltd.主要從事免疫學(xué)、分子生物學(xué)和常規(guī)生化試劑等為一體的科研產(chǎn)品銷售企業(yè),公司自成立以來,秉承""全心全意服務(wù)于科研工作者""的企業(yè)理念,立足生物科技領(lǐng)域,運(yùn)用生物技術(shù)和科研試劑,發(fā)展現(xiàn)代生物科技,為各類大中小醫(yī)院及其它醫(yī)療機(jī)構(gòu)、高等院校、科研院所、企事業(yè)單位提供優(yōu)質(zhì)的產(chǎn)品,服務(wù)生物科技領(lǐng)域的科學(xué)研究人員。
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