產(chǎn)品屬性:
產(chǎn)品名稱
規(guī)格
CAS號
型號
5-hydroxy Diclofenac
1mg 5mg
69002-84-2
EY-Y0163626
Cas No.69002-84-2
別名 N/A
化學(xué)名 N/A
分子式 C14H11Cl2NO3
分子量 312.2
溶解度 Soluble in DMSO
儲存條件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request 產(chǎn)品描述: 5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4. Diclofenac is a non-selective COX inhibitor. It inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 μM, respectively. Diclofenac inhibits ovine COX-1 and -2 with IC50 values of 60 and 220 nM, respectively.
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