中文名稱

2S-氨基-1-（磷酸二氫）-4E-十八烯-1，3R-二醇； S1P |鞘氨醇-1-磷酸；鞘氨醇-1-磷酸

英文名字

2S-amino-1-（dihydrogen phosphate）-4E-octadecene-1，3R-diol； S1P|Sphingosine-1-Phosphoric Acid； Sphingosine-1-Phosphate

供應商

開曼生物

產品貨號

62570-10

背景資料

Sphingosine-1-phosphate （S1P） is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin， it exhibits a wide range of biological activities. Not only does it enhance cell growth， but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of PKC to block apoptosis is likely due to the formation of S1P. S1P stimulates MAPK and counteracts the ceramide-induced activation of SAPK and JNK. It also increases intracellular calcium levels by both the liberation of calcium from internal stores and through activation of a Gi protein-coupled receptor resulting in the opening of a cell surface calcium channel.

產品描述

A potent lipid signaling molecule that exhibits a wide range of biological activities； it enhances cell growth and inhibits the normal apoptotic response to a variety of stimuli

保存建議

建議您在收到開曼生物品牌的Sphingosine-1-Phosphate （10 mg）產品后置于-20度保存，產品有效期為365天.

其他

開曼生物向全球科學工作者提供多研究領域的生化、免疫試劑和分析試劑盒，其產品被廣泛應用于腫瘤、氧化氮、神經學、凋亡、氧化性損傷、內分泌學等不同研究領域.開曼生物可提供用于檢測的特色試劑盒，如：類花生酸類物質、游離的生物標志、環(huán)核苷、激素及氧化氮等；也提供多種高質量試劑，包括：類花生酸類物質、氧化氮試劑及許多相關脂質、脂肪酸、酶和抗體 .