Description: Acoziborole, also known as SCYX-7158 is an orally-active compound with potent antitrypanosoma activity for the potent treatment of stage 2 human African trypanosomiasis. Human African trypanosomiasis (HAT, better called as sleeping sickness), caused by two morphologically identicalprotozoan parasite Trypanosoma bruceiis transmitted by the bite of tsetse flies of Glossinagenus, mainly in the rural areas of the sub-Saharan Africa.
Name: Acoziborole
CAS#: 1266084-51-8
Chemical Formula: C17H14BF4NO3
Exact Mass: 367.1003
Molecular Weight: 367.1066
Elemental Analysis: C, 55.62; H, 3.84; B, 2.94; F, 20.70; N, 3.82; O, 13.07
IUPAC/Chemical Name: 4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-(trifluoromethyl)benzamide
InChi Key: PTYGDEXEGLDNAZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H14BF4NO3/c1-16(2)12-6-4-10(8-14(12)18(25)26-16)23-15(24)11-5-3-9(19)7-13(11)17(20,21)22/h3-8,25H,1-2H3,(H,23,24)
SMILES Code: FC1=CC(C(F)(F)F)=C(C(NC2=CC=C(C(C)(C)OB3O)C3=C2)=O)C=C1
Appearance: Solid powder
關鍵字： 1266084-51-8;Acoziborole;
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