Name: 5-Methoxycanthinone
CAS#: 15071-56-4
Chemical Formula: C15H10N2O2
Exact Mass: 250.0742
Molecular Weight: 250.257
Elemental Analysis: C, 71.99; H, 4.03; N, 11.19; O, 12.79
Description: 5-Methoxycanthinone is an alkaloid that has been found in L. floridana and has anticancer properties. It is cytotoxic to KB, A549, and HCT-8 cells. It is active against the P. falciparum mefloquine-resistant strain F32 and the multidrug and chloroquine-resistant strain K1. However, it increases the parasite load by 68.4% in a mouse model of leishmaniasis when administered at a dose of 10 mg/kg per day.
IUPAC/Chemical Name: 5-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
InChi Key: TXEFUSAHPIYZHD-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H10N2O2/c1-19-13-8-11-14-10(6-7-16-11)9-4-2-3-5-12(9)17(14)15(13)18/h2-8H,1H3
SMILES Code: COC1=CC2=NC=CC3=C2N(C1=O)C4=C3C=CC=C4
Appearance: Solid powder
關(guān)鍵字： 15071-56-4;Methoxycanthinone;
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