Name: MO-I-500
CAS#: 1585219-04-0
Chemical Formula: C12H12ClNO5S
Exact Mass: 317.0125
Molecular Weight: 317.74
Elemental Analysis: C, 45.36; H, 3.81; Cl, 11.16; N, 4.41; O, 25.18; S, 10.09
Description: MO-I-500 is a FTO inhibitor (IC50 = 8.7 μM for purified FTO in vitro), which increases N6-methyladenosine (m6A) levels in total cellular mRNA in HeLa cells. MO-I-500 modulates levels of specific miRNAs. In a triple-negative breast cancer cell line metabolically challenged by culture without glutamine (SUM149-MA cells), MO-I-500 inhibits cell proliferation. MO-I-500 also displays anticonvulsant activity in a 6 Hz mouse model of epilepsy at nontoxic doses.
IUPAC/Chemical Name: N-(3,4-Dihydroxy-5-(4-chlorophenyl)-2-furanyl)ethanesulfonamide
InChi Key: WWHUSZQHRUNRSB-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H12ClNO5S/c1-2-20(17,18)14-12-10(16)9(15)11(19-12)7-3-5-8(13)6-4-7/h3-6,14-16H,2H2,1H3
SMILES Code: CCS(=O)(NC1=C(O)C(O)=C(C2=CC=C(Cl)C=C2)O1)=O
Appearance: Solid powder
關鍵字： 1585219-04-0;MO-I-500;
北京百奧創(chuàng)新科技有限公司是一家專注于生命科學的科技企業(yè)，由在國內科研試劑領域有著豐富從業(yè)經驗的技術團隊和管理團隊組建而成，專營進口生物試劑，科學儀器，實驗消耗品等。公司與諸多國外品牌簽下代理，RD、Abcam、CST、Genetex、Biolegend、ebioscience、polypure、polyplus、Bethyl、Novus等，能為廣大科研用戶提供數(shù)萬種試劑、儀器和實驗消耗品。
公司將不斷把上優(yōu)質的產品引入國內市場，滿足客戶的需求，公司也將緊跟生命科學的發(fā)展，為廣大科研工作者探索生命科學的奧秘奉獻綿薄之力！