Name: DPPI 1c hydrochloride
CAS#: 866396-70-5
Chemical Formula: C14H21ClN4O2
Exact Mass: 312.1353
Molecular Weight: 312.798
Elemental Analysis: C, 53.76; H, 6.77; Cl, 11.33; N, 17.91; O, 10.23
Description: DPPI 1c is an inhibitor of dipeptidyl peptidase 4. It decreased plasma glucose levels by 46 to 67% in an oral glucose challenge in fasted, diabetic KK/H1J mice when administered at doses ranging from 0.3 to 5 mg/kg.
IUPAC/Chemical Name: (2R,5S)-rel-1-[2-[[1-(hydroxymethyl)cyclopentyl]amino]acetyl]-2,5-pyrrolidinedicarbonitrile, monohydrochloride
InChi Key: RHCWAHDCHQTNBR-IWKKHLOMSA-N
InChi Code: InChI=1S/C14H20N4O2.ClH/c15-7-11-3-4-12(8-16)18(11)13(20)9-17-14(10-19)5-1-2-6-14;/h11-12,17,19H,1-6,9-10H2;1H/t11-,12+;
SMILES Code: N#C[C@@H]1N(C(CNC2(CO)CCCC2)=O)[C@H](C#N)CC1.[H]Cl
Appearance: Solid powder
關(guān)鍵字: 866396-70-5;DPPI 1c hydrochlorid;
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