中文名稱(chēng)
2-氨基-3,4-二羥基-2-(羥甲基)-14-氧代-6-二十碳烯酸; ISP-1 | Thermozymocidin; Myriocin
英文名字
2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid; ISP-1|Thermozymocidin; Myriocin
供應(yīng)商
開(kāi)曼生物
產(chǎn)品貨號(hào)
63150-5
產(chǎn)品報(bào)價(jià)
¥893.2/5mg
產(chǎn)品說(shuō)明書(shū)
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產(chǎn)品新聞
背景資料
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus (HCV) in a murine model.
產(chǎn)品描述
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A.{8482} Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. {14764} It disrupts substratum adhesion of melanoma cells.{14763} It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis.{14764,2816} Myriocin suppresses replication of the hepatitis C virus (HCV) in a murine model.{14762}
保存建議
建議您在收到開(kāi)曼生物品牌的Myriocin (5 mg)產(chǎn)品后置于-20度保存,產(chǎn)品有效期為730天.
其他
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