阿地米屈是壬二酸的合成酰胺衍生物,具有對(duì)稱的化學(xué)結(jié)構(gòu)。它被歸類為一個(gè)己二酰二胺,類似于十六酰胺乙醇。Adelmidrol發(fā)揮了重要的抗炎作用,這些作用部分依賴于PPARγ。阿地米屈可減少NF-κB轉(zhuǎn)錄和COX-2表達(dá)。
AdelMitrol is a synthetic amide derivative of azelaic acid with a symmetric chemical structure. It is classified as an adipoyl diamine, similar to hexadecanamide ethanolamine.Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ. Adelmidrol reduces NF-κB translocation, and COX-2 expression.
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