|
1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazine
|
奧拉帕尼
|
763113-22-0
|
|
4-[[4-fluoro-3-(piperazine-1-carbonyl)phenyl]Methyl]-2H-phthalazin-1-one
|
1-[5-[(3,4-二氫-4-氧代-1-酞嗪基)甲基]-2-氟苯甲?；鵠哌嗪
|
763111-47-3
|
|
(N-[(1S)-1-hydroxy-3-Methylbutyl]-Nα-(pyrazin-2-ylcarbonyl)-L-phenylalaninaMide
|
硼替佐米雜質(zhì)M
|
289472-81-7
|
|
(S)-Methyl 2-((S)-2-((S)-2-aMino-4-phenylbutanaMido)-4-MethylpentanaMido)-3-phenylpropanoate trifluoroacetic acid
|
(ALPHAS)-ALPHA-氨基苯丁?；?L-亮氨?；?L-苯丙氨酸甲酯單(三氟乙酸鹽)
|
868539-99-5
|
|
1-broMo-5-isopropoxy-2-Methyl-4-nitrobenzene
|
1-溴-5異丙氧基-2甲基-4-硝基苯
|
1202858-68-1
|
|
(R)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
OPC-345512
|
2049025-45-6
|
|
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
|
|
|
carfilzoMib interMediate iMpurity 9-2
|
|
|
|
Idelalisib iMpurity B
|
|
|
|
7-fluoro-6-nitro-quinazolin-4(3H)-one
|
7-氟-6-硝基-4-羥基喹唑啉
|
162012-69-3
|
|
7-fluoro-3,4-dihydro-quinazolin-4-one
|
7-氟-4-喹唑啉酮
|
16499-57-3
|
|
3-((3R,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
|
托法替尼
|
477600-75-2
|
|
(R)-1-(3-(4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidin-1-yl)prop-2-en-1-one
|
依魯替尼
|
936563-96-1
|
|
(S)-4-Methyl-N-((S)-1-((S)-4-Methyl-1-((R)-2- Methyloxiran-2-yl)-1 -oxopentan-2-ylaMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
卡非佐米
|
868540-17-4
|
|
(R)-4-Methyl-N-((R)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
(R)-4-甲基-N-1-(R)-4-甲基-1-(S)-2-甲基氧雜環(huán)戊烷-2-基)-1-氧代-2-基)氨基)-1-氧代-3-苯基-2-苯基-2-基-2-(R)-2-(2-嗎啉基乙酰氨基)-4-苯基丁酰胺基戊酰胺
|
|
|
(S)-4-Methyl-N-((R)-1-(((R)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
|
|
|
carfilzoMib interMediate iMpurity 1-2
|
|
|
|
ibrutinib iMpurity A
|
依魯替尼雜質(zhì)A
|
|
|
(1R)-(S)-pinanediol 1-aMMoniuM trifiuoroacetate-3-Methylbutane-1-boronate
|
(aR,3aS,4S,6S,7aR)-六氫-3a,8,8-三甲基-alpha-(2-甲基丙基)-4,6-甲橋-1,3,2-苯并二氧硼烷-2-甲胺 2,2,2-三氟乙酸鹽
|
179324-87-9
|
|
(3R,4R)-1-benzyl-N,4-diMethylpiperidin-3-aMine (2R,3R)-2,3-bis((4-Methylbenzoyl)oxy)succinic acid
|
順式-1-芐基-3-(甲氨基)-4-甲基哌啶雙鹽酸鹽
|
477600-68-3
|
|
2-fluoro-6-nitro-N-phenylbenzaMide
|
2-氟-6-硝基-N-苯基苯甲酰胺
|
870281-83-7
|
|
(2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)aMino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-diMethoxy-4a,8,13,13-tetraMethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-Methanocyclodeca[3,4]be
|
|
|
|
(4-aMino-6-chloropyriMidin-5-yl)(4-phenoxyphenyl)Methanone
|
|
|
|
(S)-tert-butyl (1-((3-fluoro-2-(phenylcarbaMoyl)phenyl)aMino)-1-oxobutan-2-yl)carbaMate
|
|
|
|
6-AMino-4-[(3-chloro-4-fluorophenyl)aMino]-7-[(S)-(tetrahydrofuran-3-yl)oxy]quinazoline
|
|
|
|
4-chloro-6-nitro-7-fluoro-quinazoline
|
4-氯-7-氟-6-硝基喹唑啉
|
162012-70-6
|
|
4-chloro-7-tosyl-7H-pyrrolo[2,3-d]pyriMidine
|
4-氯-7-甲苯磺酰基-7H-吡咯[2,3-D]嘧啶
|
479633-63-1
|
|
(S)-2-(1-((9H-purin-6-yl)aMino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
|
艾代拉里斯
|
870281-82-6
|
|
(N-[(1R)-1-hydroxy-3-Methylbutyl]-Nα-(pyrazin-2-ylcarbonyl)-L-phenylalaninaMide
|
硼替佐米雜質(zhì)2(SR異構(gòu)體,EP雜質(zhì)E)
|
289472-78-2
|
|
(S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
|
硼替佐米雜質(zhì)H
|
1446194-56-4
|
|
Methyl (4,6-diaMino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyriMidin-5-yl)carbaMate
|
N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯
|
625115-52-8
|
|
(S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate
|
CAL101 IDELALISIB N-2中間體
|
870281-85-9
|
|
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
AB005-11雜質(zhì)2
|
2049025-76-3
|
|
(S)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
|
|
|
|
(S)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
PR-059408
|
2049025-59-2
|
|
carfilzoMib interMediate iMpurity 9-3
|
|
|
|
Idelalisib iMpurity C
|
|
|
|
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
|
硼替佐米中間體2
|
114459-94-2
|
|
(3-Chloro-4-fluoro-phenyl)-(7-fluoro-6-nitro-quinazolin-4-yl)-aMine
|
N-(3-氯-4-氟苯基)-7-氟-6-硝基-4-喹唑啉胺
|
162012-67-1
|
|
(R)-2-chloro-7-ethyl-8-isopropyl-5-Methyl-7,8-dihydropteridin-6(5H)-one
|
(7R)-2-氯-7-乙基-7,8-二氫-5-甲基-8-(1-甲基乙基)-6(5H)-蝶啶酮
|
877676-50-1
|
|
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)aMino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-diMethoxy-4a,8,13,13-tetraMethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-Methanocyclodeca[3,4]be
|
卡巴他賽
|
183133-96-2
|
|
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
|
2-[(1S)-1-氨基丙基]-5-氟-3-苯基-4(3H)-喹唑啉酮
|
870281-86-0
|
|
(R)-4-((7-ethyl-8-isopropyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)aMino)-3-Methoxybenzoic acid
|
1333493-13-2
|
1333493-13-2
|
|
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9,11-dihydroxy-4,6-diMethoxy-4a,8,13,13-tetraMethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-Methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
|
7,10-二甲氧基-10-DAB III
|
183133-94-0
|
|
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
|
1-(2-氟芐基)-1H-吡唑并[3,4-B]吡啶-3-甲腈
|
256376-65-5
|
|
(S)-tert-butyl (1-(2-fluoro-6-nitro-N-phenylbenzaMido)-1-oxobutan-2-yl)carbaMate
|
CAL-101(N-1)中間體
|
870281-84-8
|
|
(R)-4-Methyl-N-((R)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
|
|
|
(S)-4-Methyl-N-((R)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
|
|
|
carfilzoMib interMediate iMpurity 1-3
|
|
|
|
ibrutinib iMpurity B
|
依魯替尼雜質(zhì)B
|
|
|
2-aMino-6-fluorobenzoic acid hydrochloride
|
2-氨基-6-氟苯甲酸鹽酸鹽
|
78755-93-8
|
|
2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyriMidine-4,5,6-triaMine
|
2-[1-[(2-氟苯基基)甲基]-1H-吡唑并[3
|
428854-24-4
|
|
(E)-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(phenyldiazenyl)pyriMidine-4,6-diaMine
|
立奧西瓜中間體6
|
428854-23-3
|
|
(S)-2-aMino-4-Methyl-1-((R)-2-Methyloxiran-2-yl)pentan-1-one trifluoroacetic acid
|
(2S)-2-氨基-4-甲基-1-[(2R)-2-甲基環(huán)氧乙烷基]-1-戊酮
|
247068-84-4
|
|
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3R)-3-((tert-butoxycarbonyl)aMino)-3-phenyl-2-((triethylsilyl)oxy)propanoyl)oxy)-11-hydroxy-4,6-diMethoxy-4a,8,13,13-tetraMethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-Methanocyc
|
|
|
|
(IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt
|
(IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt
|
789472-91-9
|
|
(S)-tert-butyl 3-(4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidine-1-carboxylate
|
|
|
|
carfilzoMib iMpurity -A
|
卡非左米雜質(zhì)A
|
|
|
4-Methyl-3-((4-(3-pyridinyl)-2-pyriMidinyl)aMino)-N-(5-(4-Methyl-1H-iMidazol-1-yl)-3-(trifluoroMethyl)phenyl)benzaMide
|
尼羅替尼
|
641571-10-0
|
|
4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]benzoic acid
|
4-甲基-3-[[4-(3-吡啶基)-2-嘧啶基]氨基]苯甲酸
|
641569-94-0
|
|
Methyl (4,6-diaMino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyriMidin-5-yl)(Methyl)carbaMate
|
利奧西呱
|
625115-55-1
|
|
Methyl4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate
|
4-甲基-3-[[4-(3-吡啶基)-2-嘧啶基]氨基]苯甲酸甲酯
|
917392-54-2
|
|
4-[(3-chloro-4-fluorophenyl)aMino]-6-{[4-(N,N-diMethylaMino)-1-oxo-2-buten-1-yl]aMino}-7-((S)-tetrahy-drofuran-3-yloxy)-quinazoline
|
阿法替尼
|
850140-72-6
|
|
N-((3R,4R)-1-benzyl-4-Methylpiperidin-3-yl)-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
|
N-甲基-N-((3R,4R)-4-甲基-1-芐基-3-哌啶基)-7H-吡咯并[2,3-D]嘧啶-4-胺
|
477600-73-0
|
|
1-[[(2S)-1-oxo-3-phenyl-2[(pyrazinylcarbonyl)aMino]propyl]aMino]pentylboronic anhydride
|
脫氧異丁基-正丁基硼替佐米
|
1104011-35-9
|
|
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
|
硼替佐米雜質(zhì)
|
289472-80-6
|
|
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxiMidaMide
|
1-(2-氟芐基)-1H-吡唑并[3,4-B]吡啶-3-甲脒
|
256376-68-8
|
|
1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone
|
2-甲氧基-4-(N-乙?；?哌嗪-1-基)苯胺
|
1021426-42-5
|
|
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
AB005-11雜質(zhì)
|
2049025-67-2
|
|
(4,6-dichloropyriMidin-5-yl)(4-phenoxyphenyl)Methanol
|
|
|
|
(S)-Methyl 2-((S)-2-aMino-4-MethylpentanaMido)-3-phenylpropanoate trifluoroacetic acid
|
|
38115-18-9
|
|
1-benzyl-4-(5-isopropoxy-2-Methyl-4-nitrophenyl)pyridin-1-iuM broMide
|
|
|
|
Idelalisib iMpurity D
|
|
|
|
(2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one
|
(E)-3-(二甲基氨基)-1-(吡啶-3-基)丙-2-烯-1-酮
|
123367-26-0
|
|
(3S,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine (2S,3S)-2,3-bis((4-Methylbenzoyl)oxy)succinic acid
|
(2R,3R)-2,3-雙[(4-甲基苯甲?；?氧基]丁二酸和 (3R,4R)-N,4-二甲基-1-(苯基甲基)-3-哌啶胺的化合物
|
477600-71-8
|
|
3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
|
伊布替尼中間體N-2
|
330786-24-8
|
|
5-chloro-N2-(2-isopropoxy-5-Methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyriMidine-2,4-diaMine hydrochloride
|
雙鹽酸鹽色瑞替尼
|
1380575-43-8
|
|
(R)-4-Methyl-N-((R)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
(R)-4-甲基-N-((R)-1-(((S)-4-甲基-1-((R)-2-甲基環(huán)氧乙烷-2-基)-1-氧代戊烷-2-基基)氨基)-1-氧代-3-苯基丙-2-基)-2-((S)-2-(2-嗎啉代)-4-苯基丁酰胺基)戊酰胺
|
|
|
(S)-4-Methyl-N-((R)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
PR-187
|
2049025-49-0
|
|
carfilzoMib interMediate iMpurity 9-1
|
|
|
|
Idelalisib iMpurity A
|
|
|
|
(1S,2S,3R,5S)-pinanedioxy-N-pyrazinoyl-D-phenylalanyl-L-leucineboronate
|
保特佐米蒎烷二醇酯
|
205393-22-2
|
|
5-chloro-N2-(2-isopropoxy-5-Methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyriMidine-2,4-diaMine
|
色瑞替尼
|
1032900-25-6
|
|
(3R,4R)-1-benzyl-N,4-diMethylpiperidin-3-aMine hydrochloride
|
(3R,4R)-1-芐基-N,4- 二甲基哌啶-3-胺鹽酸鹽
|
493040-24-7
|
|
(R)-4-Methyl-N-((R)-1-(((R)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
|
|
|
|
(S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enaMide
|
|
|
|
carfilzoMib interMediate iMpurity 1-1
|
|
|
|
N-(2-Pyrazinecarbonyl)-L-phenylalanine-L-leucine boronic anhydride
|
硼替佐米
|
179324-69-7
|
|
5-(4-Methyl-1H-iMidazol-1-yl)-3-(trifluoroMethyl)-BenzeneaMine
|
3-(4-甲基-1H-咪唑-1-基)-5-(三氟甲基)苯胺
|
641571-11-1
|
|
2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)-Methyl)benzoic acid
|
5-[(3,4-二氫-4-氧代-1-酞嗪基)甲基]-2-氟苯甲酸
|
763114-26-7
|
|
Cis-4-?[4-?(cyclopropylMethyl)?-?1-?piperazinyl]?-?cyclohexanaMine hydrochloride (1:?)
|
(1S,4S)-4-(4-(環(huán)丙基甲基)哌嗪-1-基)環(huán)己胺
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755039-90-8
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4-(5-isopropoxy-2-Methyl-4-nitrophenyl)pyridine
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4-(5-異丙氧基-2-甲基-4-硝基-苯基)-吡啶
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1032903-62-0
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Methyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbiMidate
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利奧西呱中間體
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304874-06-4
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(S)-2-((S)-4-Methyl-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMido)-3-phenylpropanoic acid
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卡非佐米中間體
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868540-16-3
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(S)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
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(S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((S)-2-METHYLOXIRAN-2-YL)-1-OXOPENTAN-2-YL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO)PENTANAMIDE
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1672698-88-2
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tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate
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(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
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1187479-72-6
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(4,6-dichloropyriMidin-5-yl)(4-phenoxyphenyl)Methanone
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(S)-Methyl 2-((S)-4-Methyl-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMido)-3-phenylpropanoate
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2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride
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2-氨基-6-氟-N-苯基苯胺
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1417456-04-2
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(E)-2-(phenyldiazenyl)Malononitrile
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苯基偶氮丙二腈
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6017-21-6
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