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CAS RN: 67-30-1 | Product Number: T3730
3,3',5,5'-Tetraiodothyroacetic Acid
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetic Acid
- 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylacetic Acid
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 100MG |
$229.00
|
2 | Contact Us | 6 |
|
| 500MG |
$695.00
|
1 | Contact Us | 34 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | T3730 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__4H__8I__4O__4 = 747.83 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 500MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 67-30-1 |
| Reaxys Registry Number | 2173215 |
| PubChem Substance ID | 468592913 |
| MDL Number | MFCD00055932 |
Specifications
| Appearance | White to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 230 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | CY1585800 |
Transport Information:
| UN Number (DOT-AIR) | UN2811 |
| Class (DOT-AIR) | 6.1 |
| Packing Group (TCI-A) | I |
| HS Number | 2916.39.7900 |
Application
3,3',5,5'-Tetraiodothyroacetic Acid: A Thyroid Hormone Analogue with Anti-Angiogenesis and Anti-Tumor Growth Effects
3,3',5,5'-Tetraiodothyroacetic acid is a thyroid hormone (L-thyroxine [T0245]) analogue. It is reported that 3,3',5,5'-tetraiodothyroacetic acid acts at a cell surface receptor to block angiogenic and tumor cell proliferation action of thyroid hormones, which have been recently shown to induce tumor growth and angiogenesis. (The product is for research purpose only.)
References
- Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor
- Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid
- Metabolic Effects of Thyroid Hormone Derivatives (a review)
- Determination of levothyroxine and its degradation products in pharmaceutical tablets by HPLC-UV-ICP-MS
Articles/Brochures
TCIMAIL
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